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Quantitative Optical Sensor Findings in Head & Neck Squamous Cell Carcinoma

NCT02943044 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2017-03-03

No results posted yet for this study

Summary

The goal of this study is to determine the optical spectroscopy characteristics of tumor in patients with head and neck squamous cell carcinoma (HNSCC). HNSCC constitutes over 90% of all head and neck cancers. These spectroscopy measurements will be compared with pathological diagnosis of tissue biopsies from the same site. These readings will be performed in the operating room during routine endoscopy with biopsy and tumor mapping of patients who have a suspected squamous cell carcinoma of the head and/or neck. Furthermore, a built in pressure sensor will be used to compare biopsy sites with their benign counterparts. If successful, the optical measurements could be used to survey for and delineate the extent of malignancies in a noninvasive manner. This would be especially helpful for clinic visits where suspicious lesions are seen and would otherwise require biopsy for diagnosis. Immediate benefits would include patients with unknown primaries in which numerous directed biopsies are obtained from multiple head and neck sites.

Conditions

Interventions

DEVICE

No intervention, this is an observational study

Non interventional, non-invasive measurements of tissue samples suspected of squamous cell carcinoma using an optical probe.

Sponsors & Collaborators

  • Duke University

    collaborator OTHER

  • National Cancer Institute (NCI)

    collaborator NIH

  • Zenalux Biomedical, Inc.

    lead INDUSTRY

Principal Investigators

  • Walter Lee, MD · Duke University

Eligibility

Min Age
24 Years
Max Age
89 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-12-31
Primary Completion
2017-12-31
Completion
2017-12-31

Countries

  • United States

Study Locations

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Diseases
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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02943044 on ClinicalTrials.gov