Real-world Analysis on the Efficacy and Safety of Neoadjuvant Therapy for Head and Neck Squamous Cell Carcinoma (neoHNSCC)
NCT06011993 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 30
Last updated 2023-08-25
Summary
This is a retrospective, single-arm study that assesses the efficacy and safety of neoadjuvant immunotherapy combined with platinum-based chemotherapy for Head and Neck Squamous Cell Carcinoma. This trial will also explore the biomarkers of neoadjuvant immunochemotherapy.
Conditions
Sponsors & Collaborators
-
Second Affiliated Hospital, School of Medicine, Zhejiang University
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-07-19
- Primary Completion
- 2023-12-01
- Completion
- 2023-12-01
Countries
- China
Study Locations
More Related Trials
-
Trial of Neoadjuvant Therapy With Paclitaxel and Carboplatin in Operable Locally Advanced Head and Neck Cancer Patients
NCT05294900 ·Status: UNKNOWN ·Phase: PHASE2
-
Reducing Excision Margins After Neoadjuvant Chemoimmunotherapy for HPV Negative Resectable Locally Advanced HNSCC
NCT05459415 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Study of Chemo-Immunotherapy in Head and Neck Cancer Patients
NCT01149902 ·Status: UNKNOWN ·Phase: PHASE1
-
Efficacy and Safety of PD-1 Plus Chemotherapy in Poorly Differentiated Locally Advanced (LA) HNSCC
NCT06100497 ·Status: RECRUITING ·Phase: PHASE2
-
The Efficacy and Safety of Pucotenlimab Combined With TP Chemotherapy as Neoadjuvant Therapy for Locally Advanced HNSCC
NCT06895369 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Effects of Neoadjuvant Therapy With Carboplatin, Paclitaxel Combined With Anti-PD-1 Drugs on Cognitive Function in Patients With Resectable Head and Neck Squamous Cell Carcinoma
NCT06576180 ·Status: RECRUITING
-
Tislelizumab Combined With Chemotherapy for Different Cycles of Neoadjuvant Therapy for Locally Advanced Resectable Squamous Cell Carcinoma of the Head and Neck (NeoTempo)
NCT07147426 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Neoadjuvant Chemotherapy, Tislelizumab With Afatinib for HNSCC
NCT05516589 ·Status: COMPLETED ·Phase: PHASE2
-
Neoadjuvant Tislelizumab Plus Chemotherapy for Resectable Locally-advanced Head and Neck Squamous Cell Carcinoma
NCT06235918 ·Status: RECRUITING ·Phase: PHASE2
-
Neoadjuvant Adebrelimab Plus Dalpiciclib in Head and Neck Squamous Cell Carcinoma
NCT06199271 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Study of Pharmacokinetic, Safety, Immunogenicity and Efficacy of CMAB819 and Nivolumab in R/M HNSCC
NCT04659369 ·Status: TERMINATED ·Phase: PHASE1
-
the Study of Effect of Chronomodulated Chemotherapy on the Dendritic Cells Subsets in the Treatment of Advanced Nasopharyngeal Cancer
NCT03196869 ·Status: UNKNOWN ·Phase: PHASE2
-
Adelbelimab Combination Chemotherapy in Neoadjuvant Therapy for Squamous Cell Carcinoma of the Head and Neck
NCT06016413 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Docetaxel/Pembrolizumab in Head and Neck Squamous Cell Carcinoma
NCT05252429 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Comparing Neoadjuvant Chemotherapy Combined With PD-1 Inhibitor Versus Neoadjuvant Chemotherapy in Locally Advanced Laryngeal and Hypopharyngeal Carcinoma
NCT06957938 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
Neoadjuvant Anti-PD-1 Antibody (Toripalimab) or Combined With Chemotherapy in HNSCC Patients
NCT04164238 ·Status: UNKNOWN ·Phase: PHASE2
-
Safety and Efficacy of SCT-I10A in Head and Neck Squamous Cell Carcinoma
NCT04146181 ·Status: UNKNOWN ·Phase: PHASE2
-
Neoadjuvant Toripalimab + Chemotherapy ± Cetuximab in Locally Advanced Head and Neck Squamous Cell Carcinoma (Neo-ICT)
NCT06647563 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
Postoperative Concurrent Chemoradiotherapy With Docetaxel for High-Risk Squamous Cell Carcinoma of Head and Neck
NCT02776137 ·Status: COMPLETED ·Phase: PHASE2
-
A Clinical Trial to Evaluate Effect of IAE0972 Combined with Chemotherapy for R/M HNSCC or NPC(Note: It is Currently Phase II.).
NCT06719479 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2/PHASE3
-
CD40 Agonist and PD-1 Inhibitor in HNSCC
NCT06159621 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Phase II Multi-centered Study of Perioperative Ivonescimab Versus Pembrolizumab Combined with Standard of Care (SOC) in Patients with Resectable, Locally Advanced Head and Neck Squamous Cell Carcinoma
NCT06814067 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Effects of Neoadjuvant Therapy With Carboplatin, Paclitaxel Combined With Anti-PD-1 Drugs on Pain, Anxiety and Depression in Patients With Resectable Head and Neck Squamous Cell Carcinoma
NCT06575322 ·Status: RECRUITING
-
A Study of Nimotuzumab Plus Adebrelimab With Chemotherapy in Cisplatin-Ineligible Patients With Head And Neck Squamous Cell Carcinoma
NCT07105592 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Pembrolizumab in Combination With Low-dose PFas Neoadjuvant Treatment for Locally Advanced HNSCC
NCT05446467 ·Status: RECRUITING ·Phase: PHASE2