A study in Health and Quality of Life Outcomes found speech dysfunction is the dominant early determinant of postoperative quality of life in oral cancer patients, with significant direct and indirect effects through psychosocial pathways.
Two clinical trials demonstrate efficacy of talimogene laherparepvec (T-VEC) oncolytic virus therapy in HER2-negative breast cancer and nonmelanoma skin cancers, with favorable safety profiles and durable responses in subset of patients.
A comprehensive market report reveals over 180 companies are developing more than 200 PD-1 and PD-L1 inhibitor drugs, with recent fast-track designations and successful Phase III trial results driving expansion in cancer immunotherapy.
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|---|---|---|---|
| NCT07773688 |
Two-photon Fluorescence Microscopy of Dermatologic Biopsies |
RECRUITING | NA |
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Study Evaluating the Safety and Feasibility of Panitumumab-IRDye800 and [18F]NOTA-ABY-030 for Targeted Dual-Modality Imaging (TDMI) in Head and Neck Squamous Cell Carcinoma |
NOT_YET_RECRUITING | PHASE1 |
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Impact of Dysport on PMFF Donor Scar |
NOT_YET_RECRUITING | PHASE4 |
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Oral Mucositis Management in Patients Receiving Radiation for Head and Neck Cancer: An Evaluation of a Barrier Based Treatment |
ACTIVE_NOT_RECRUITING | PHASE4 |
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Phase 1 Study Of TROP2 CAR/IL-15 TGFBR2 KO NK Cell In Patients With Oral Premalignant Lesions |
NOT_YET_RECRUITING | PHASE1 |
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Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors |
RECRUITING | EARLY_PHASE1 |
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A Study of IDP-001 in Advanced or Metastatic Solid Tumors |
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AI-Assisted Endoscopy for Upper Aerodigestive Tract Lesions |
NOT_YET_RECRUITING | |
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Combining Neo-adjuvant ATR-inhibition With Nodal SBRT for Early-stage Resectable HPV+ OPSCCs |
NOT_YET_RECRUITING | PHASE1/PHASE2 |
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Omission of Postoperative Radiation in HPV-Associated Oropharyngeal Cancer Using ctHPVDNA Surveillance (OPERATION) |
RECRUITING | PHASE2 |
