Two clinical trials demonstrate efficacy of talimogene laherparepvec (T-VEC) oncolytic virus therapy in HER2-negative breast cancer and nonmelanoma skin cancers, with favorable safety profiles and durable responses in subset of patients.
A comprehensive market report reveals over 180 companies are developing more than 200 PD-1 and PD-L1 inhibitor drugs, with recent fast-track designations and successful Phase III trial results driving expansion in cancer immunotherapy.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07602842 |
A Study of IDP-001 in Advanced or Metastatic Solid Tumors |
NOT_YET_RECRUITING | PHASE1/PHASE2 |
| NCT07596355 |
AI-Assisted Endoscopy for Upper Aerodigestive Tract Lesions |
NOT_YET_RECRUITING | |
| NCT07578467 |
Combining Neo-adjuvant ATR-inhibition With Nodal SBRT for Early-stage Resectable HPV+ OPSCCs |
NOT_YET_RECRUITING | PHASE1/PHASE2 |
| NCT07513389 |
Omission of Postoperative Radiation in HPV-Associated Oropharyngeal Cancer Using ctHPVDNA Surveillance (OPERATION) |
RECRUITING | PHASE2 |
| NCT07403630 |
INTEGRATIVE "MULTI-OMICS" AND FUNCTIONAL PLATFORM FOR THE COMPLETE DIAGNOSTIC CHARACTERIZATION OF TUMORS: THE ITALIAN TUMOR CHEMOGENOMIC PROFILER (IT-TCP) |
RECRUITING | NA |
| NCT07361133 |
Cyclophosphamide and Etoposide as a Metronomic Therapy in Advanced Head and Neck Squamous Cell Cancer |
NOT_YET_RECRUITING | PHASE2 |
| NCT07346196 |
A Trial of Locoregionally Advanced Squamous Cell Carcinoma of The Head and Neck |
NOT_YET_RECRUITING | PHASE2 |
| NCT07285044 |
The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas |
RECRUITING | PHASE2 |
| NCT07241585 |
Vitamin D Effects on Immune Microenvironment of Nonmelanoma Skin Cancer After Photodynamic Therapy (PDT) |
NOT_YET_RECRUITING | NA |
| NCT07223424 |
Patient Preference for Subcutaneous vs. Intravenous Immune Therapy |
RECRUITING | PHASE2 |
