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Taste Physiology in Obese Volunteers Before and After Bariatric Surgery

NCT02902198 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 16

Last updated 2025-04-03

No results posted yet for this study

Summary

The objective is to investigate neuro-anatomical correlates of gastrointestinal taste stimulation by means of functional MRI before and after bariatric surgery. Intragastric administration of glucose, monosodium glutamate, chloroquine and placebo is followed by functional brain MRI in obese humans before and 3 months after surgery.

Conditions

Interventions

DIETARY_SUPPLEMENT

Placebo

Tap water 200ml

DIETARY_SUPPLEMENT

Glucose

25g Glucose in 200ml tap water

DIETARY_SUPPLEMENT

Monosodium glutamate

1g monosodium glutamate in 200ml tap water

DIETARY_SUPPLEMENT

Quinine

17mg quinine in 200ml tap water

Sponsors & Collaborators

  • University Hospital, Basel, Switzerland

    lead OTHER

Principal Investigators

  • Christoph Beglinger, Prof · University Basel

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-12-31
Primary Completion
2026-12-31
Completion
2027-12-31

Countries

  • Switzerland

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02902198 on ClinicalTrials.gov