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The Acute Effect of Two Berry Extracts on Cognition and Mood in Adults Aged 40 to 60

NCT02810769 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2016-06-23

No results posted yet for this study

Summary

The first study of my PhD showed that acute supplementation of berry extracts can modulate cognitive behaviour in healthy adults. There is a growing body of evidence supporting an improvement in memory and learning performance in animal models following the ingestion of flavonoid rich fruits (Shukitt-Hale et al 2008;Spencer 2008; Spencer et al., 2008). However, study 2, showed no effect on any aspects of memory in healthy young adults after supplementation of the berry extracts. It is hypothesised that the lack of behavioural effects on memory of the berry juice in study 2 was because of the cohort used. These healthy adult participants were already performing near to their peak (Salthouse et al., 2009), and unlike study one, participants were not mentally fatigued enough to reveal subtle cognitive benefits.

The aims of the study are to examine if acute supplementation of two berry extracts in an older population can augment memory, attention and executive function. Secondly, the time course of these behavioural effects will be measured by multiple cognitive assessments throughout the day after consumption of the extracts.

Conditions

  • Ageing

Interventions

DIETARY_SUPPLEMENT

Berry drink

Cold pressed berry drink standardised to contain 500mg of berry polyphenols

DIETARY_SUPPLEMENT

Control

Sugar matched control containing berry flavouring and no phytochemicals

DIETARY_SUPPLEMENT

Powdered berry drink

Berry drink made from a powder concentrate standardised to contain 500mg of polyphenols

Sponsors & Collaborators

  • The New Zealand Institute of Plant and Food Research Ltd.

    collaborator OTHER_GOV

  • Northumbria University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
40 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-11-30
Primary Completion
2013-05-31
Completion
2013-05-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02810769 on ClinicalTrials.gov