MedTrace Logo

Brain Plasticity of Autism in Response to Early Behavioral Intervention: A Multimodal MRI Study

NCT02807766 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 150

Last updated 2024-01-16

No results posted yet for this study

Summary

Autism is a well-recognized neurodevelopmental disorder severely affecting the health of children. While the unclear neurobiological basis of autism and the lack of effective medication, the most commonly used approach for treatment is behavioral intervention. However, the pathophysiological mechanisms underlying the intervention therapy remains incompletely understood. The current project aims to explore the impacts of different early behavioral intervention methods on brain plasticity of autism using multimodal MRI technique and provide guidelines for the intervention and treatment of autism by evaluating the efficiency of these methods.

Conditions

Interventions

BEHAVIORAL

Behavior modification

Each group has 30 subjects and experiences six months' training.

BEHAVIORAL

Behavior modification and sensory integration training

Each group has 30 subjects and experiences six months' training.

BEHAVIORAL

Behavior modification and applied behavioral analysis

Each group has 30 subjects and experiences six months' training.

BEHAVIORAL

Behavior modification and TEACCH

Each group has 30 subjects and experiences six months' training.

Sponsors & Collaborators

  • University of Electronic Science and Technology of China

    lead OTHER

Principal Investigators

  • Huafu Chen · School of Life Science and Technology, University of Electronic Science and Technology of China

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
FACTORIAL

Eligibility

Min Age
2 Years
Max Age
8 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-05-31
Primary Completion
2024-12-31
Completion
2024-12-31

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02807766 on ClinicalTrials.gov