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Understanding the Mechanisms of Autism : an MRI and Social Cognition Study

NCT06334588 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 160

Last updated 2025-12-23

No results posted yet for this study

Summary

The main goal of this study is to investigate anatomo-functional brain abnormalities associated with autism spectrum disorders using a multimodal brain imaging approach, as well as its links to social cognition difficulties measured using eye-tracking

Conditions

Interventions

DIAGNOSTIC_TEST

MRI

Anatomical and functional images will be acquired and review by an experienced neuro-radiologist

DEVICE

Eye-tracking

Eye movements and follow a person's gaze will be recorded during visualization of stimuli presented in the screen by analyzing images of the eye captured by an infrared camera

OTHER

Clinical Scales

CGI, E-CAR and ABC will be used for behavior and clinical evaluation

GENETIC

Research of genetic anomalies

For the diagnosis of autism, patients benefit from a a genetic assessment. This is carried out as part of their care

Sponsors & Collaborators

  • URC-CIC Paris Descartes Necker Cochin

    collaborator OTHER

  • Assistance Publique - Hôpitaux de Paris

    lead OTHER

Principal Investigators

  • Monica ZILBOVICIUS · INSERM INSERM ERL "Trajectoires Développementales en Psychiatrie"

Study Design

Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
3 Months
Max Age
28 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-04-17
Primary Completion
2029-04-30
Completion
2031-04-30

Countries

  • France

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06334588 on ClinicalTrials.gov