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Study of Progression of Community Acquired Pneumonia in the Hospital

NCT02782013 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 2309

Last updated 2022-10-17

No results posted yet for this study

Summary

Pneumonia is a common infectious disease of the lung, often requiring treatment in the hospital. Clinical scoring systems are available, identifying patients not requiring hospitalization. However, the course of disease of patients in the hospital remains hard to predict. While most patients will recover quickly, some will, despite appropriate treatment, develop a severe course leading to sepsis and systemic responses resulting in organ dysfunction. The PROGRESS study aims to identify clinical, genetic, and other molecular markers and combinations thereof predicting a severe course of pneumonia in the hospital. Such predictors will, for instance, support decisions on earlier transfer of patients to intensive care and thus improving outcome.

Conditions

Sponsors & Collaborators

  • University of Leipzig

    collaborator OTHER

  • Jena University Hospital

    collaborator OTHER

  • University of Giessen

    collaborator OTHER

  • University Medicine Greifswald

    collaborator OTHER

  • Charite University, Berlin, Germany

    collaborator OTHER

  • German Federal Ministry of Education and Research

    collaborator OTHER_GOV

  • Pneumonia Research Network on Genetic Resistance and Susceptibility for the Evolution of Severe Seps

    lead OTHER

Principal Investigators

  • Norbert Suttorp, MD · Charite University, Berlin, Germany

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-08-25
Primary Completion
2022-06-01
Completion
2022-06-01

Countries

  • Austria
  • Germany

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02782013 on ClinicalTrials.gov