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AMblyopia Treatment Through PErceptual Training in Children (AMPEL)

NCT02555384 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL

Last updated 2023-06-23

No results posted yet for this study

Summary

Amblyopia, affects 4% of the population. In the presence of a normal retina and optic nerve, the visual cortex does not develop normally secondary to the amblyopic eye being at a disadvantage in the sensitive period such as in strabismus. Amblyopia is associated with visuospatial disorders, and poor to absent stereopsis. Amblyopia is treated by occlusion of the non- amblyopic eye in childhood. The present study aims to evaluate the effectiveness of perceptual learning (PL), that is a training of visual drawing tasks (12 sessions of 30 Minutes duration) with crowding (c) for children with amblyopia compared to an amblyopic control group with a placebo drawing task.

Arm 1: Crowded (PLc)- Training with small spacing Arm 2: Uncrowded (PLu)- Training with large spacing Prior to this, a small group will help optimize parameters such as contrast and distance of visual objects presented

Conditions

  • Strabismic Amblyopia

Interventions

OTHER

crowded drawing task

Marking inverted signs on a sheet where symbols are presented close to one another

OTHER

uncrowded drawing task

Marking inverted signs on a sheet where there is a larger distance between symbols

Sponsors & Collaborators

  • University Medical Center Nijmegen

    collaborator OTHER

  • University of Basel

    lead OTHER

Principal Investigators

  • Anja M Palmowski-Wolfe, Prof. med. · University Basel, Eye Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
4 Years
Max Age
8 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-01-31
Primary Completion
2020-11-30
Completion
2020-11-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02555384 on ClinicalTrials.gov