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The Anabolic Effect Of Perioperative Nutrition With Insulin In Patients Undergoing CABG

NCT02549443 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2015-09-15

No results posted yet for this study

Summary

This study evaluates whether providing a nutritional intervention in the form of insulin, sugar and protein during and after open-heart surgery will increase the body's protein stores and maintain a normal level of blood sugar. The primary outcome will be Whole body protein balance which will be assessed by isotope tracer kinetics. Protein balance will be calculated as protein synthesis minus protein breakdown with positive values indicating anabolism and negative values catabolism. The preoperative measurements will be performed on the morning before the operation. Postoperative studies will be conducted two hours after surgery in the intensive care unit. Patients will be followed for 12 hours after surgery.

Conditions

Interventions

DIETARY_SUPPLEMENT

Amino acids

AA (Travasol Baxter, Deerfield IL) during and after surgery in an amount equivalent to 20% and 35% of the patient's energy expenditure (EE)

Sponsors & Collaborators

  • McGill University Health Centre/Research Institute of the McGill University Health Centre

    lead OTHER

Principal Investigators

  • Roupen Hatzakorzian, MD, MSc · McGill University Health Centre/Research Institute of the McGill University Health Centre

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-08-31
Primary Completion
2015-05-31
Completion
2015-06-30

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02549443 on ClinicalTrials.gov