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Clinical Efficacy of Fluoride Toothpastes Using an In Situ Caries Model

NCT02436473 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL

Last updated 2015-08-13

No results posted yet for this study

Summary

The purpose of this study is to evaluate the effect of the test toothpaste containing 1150 parts per million (ppm) of fluoride (F) on the mineral content of demineralized enamel specimens, in an in situ caries model system, by comparing the differences in net remineralization change (ΔM) following use of the test toothpaste with a fluoride free (0 ppm F) reference control toothpaste.

Conditions

  • Dental Caries

Interventions

DRUG

Toothpaste containing 1150ppm F

US marketed toothpaste containing 1150ppm of F

OTHER

Toothpaste containing 0ppm F

Experimental toothpaste containing 0ppm F

DRUG

Toothpaste containing 250ppm F

Experimental toothpaste containing 250ppm F

DRUG

Toothpaste containing 1150ppm F

Experimental toothpaste containing 1150ppm F

Sponsors & Collaborators

Principal Investigators

  • GSK Clinical Trials · GlaxoSmithKline

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-12-31
Primary Completion
2016-11-30
Completion
2016-11-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02436473 on ClinicalTrials.gov