Women's Health Initiative Strong and Healthy Study

Summary

The WHISH trial applies state-of-the science behavioral principles and currently available technologies to deliver a physical activity intervention without face-to-face contact to \~25,000 older U.S. women expected to consent. It includes the National Institute of Aging (NIA) Go4Life® Exercise \& Physical Activity materials 3 and WHISH developed targeted materials based on Go4Life® to provide inspirational tips and recommendations about how to achieve nationally recommended levels of PA and overcome barriers to exercise, with a means for self-monitoring and setting personal goals. The intervention builds upon evidence-based behavioral science principles and intervention components that have proven to be effective in increasing PA in older women, with innovative adaptive approaches to tailoring the delivery to meet individual (personal) needs.

Conditions

• Myocardial Infarction
• Stroke
• Cardiovascular Mortality
• Hip Fractures
• Falls
• Mortality
• Venous Thromboembolic Event
• Peripheral Artery Disease
• Physical Function
• Coronary Revascularization
• Mobility and Independence
• Clinical (Non-hip) Fractures
• Sleep
• Depressive Symptoms

Interventions

BEHAVIORAL

Physical Activity

The PA intervention will consist of a multimodal activity program of aerobics, balance, strength, flexibility. The intervention will involve encouraging participants to increase all forms of PA throughout the day and to decrease sedentary time, such as sitting. This may include activities such as leisure sports, gardening, use of stairs instead of escalators, leisurely walks with friends, and less use of remote control devices.The intervention is conducted primarily by mail with website support and resources available.

Sponsors & Collaborators

• University of California, San Diego

  collaborator OTHER

• Stanford University

  collaborator OTHER

• National Heart, Lung, and Blood Institute (NHLBI)

  collaborator NIH

• Fred Hutchinson Cancer Center

  lead OTHER

Principal Investigators

• Charles L Kooperberg, PhD · Fred Hutchinson Cancer Center

• Andrea Z LaCroix, PhD · University of California, San Diego

• Marcia L Stefanick, PhD · Stanford University

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

66 Years

Max Age

99 Years

Sex

FEMALE

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2015-04-02

Primary Completion

2024-12-31

Completion

2024-12-31