A Home-Based Prehabilitation Exercise Intervention for Improving Physical Function in Patients With Bladder Cancer and Upper Tract Urothelial Cancer, Get Moving Trial

Summary

Prehabilitation refers to the process of improving a patient's functional capabilities prior to a surgical procedure with the goal of decreasing post-surgical inactivity and physical decline. This clinical trial evaluates the utility of a personalized home-based prehabilitation exercise intervention for the improvement of physical function and surgical outcomes in patients with urothelial carcinoma undergoing definitive or consolidative surgery of the bladder (radical cystectomy) or upper tract (nephroureterectomy, ureterectomy) with or without preceding neoadjuvant/systemic therapy. The exercise intervention includes at-home exercise sessions focused on the improvement of core strength and balance as well as personalized step count goals, delivered to patients remotely via a smart-device-based application (ExerciseRx). Encouraging physical activity before surgery may improve physical function and surgical outcomes in patients who are scheduled to undergo surgery for their bladder or urothelial cancer.

Conditions

• Bladder Cancer
• Urothelial Carcinoma
• Upper Tract Urothelial Carcinoma
• Renal Pelvis and Ureter Urothelial Carcinoma

Interventions

OTHER

Best Practice

Receive SOC educational materials

OTHER

Exercise Intervention

Receive (P)REHAB exercise program

OTHER

App-Based Intervention

Use ExerciseRx app

OTHER

App-Based Intervention

Use FitBit app

OTHER

Interview

Ancillary studies

OTHER

Wearable Activity Tracker

Wear FitBit

OTHER

Physical Performance Testing

Ancillary studies

OTHER

Questionnaire Administration

Ancillary studies

Sponsors & Collaborators

• Bladder Cancer Advocacy Network

  collaborator OTHER

• University of Washington

  lead OTHER

Principal Investigators

• Sarah Psutka · Fred Hutch/University of Washington Cancer Consortium

Study Design

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2023-12-19

Primary Completion

2027-04-30

Completion

2027-04-30

Countries

• United States

Study Locations