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Human Clinical Trial of Uterine Transplantation in the United Kingdom

NCT02388802 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2016-11-08

No results posted yet for this study

Summary

Ten patients will undergo uterine transplantation.

Conditions

Interventions

PROCEDURE

Oocyte retrieval and freezing

10 Patients will undergo oocyte retrieval and freezing

PROCEDURE

Deceased Donor Allograft Excision

Appropriately matched uterine transplant allografts will be excised from deceased donors

PROCEDURE

Uterine Transplantation

Following egg freezing the patients will undergo uterine transplant from deceased donors

DRUG

Immunosuppressive Agents

Patients will be appropriately immunosuppressed, whilst being closely monitored clinically, radiologically and immunologically.

PROCEDURE

In-vitro fertilisation

12 months after successful transplantation,the patients will undergo IVF

PROCEDURE

Caesarean Section

Following successful conception and antenatal period, the babies will be born by Caesarean Section

Sponsors & Collaborators

  • Imperial College London

    collaborator OTHER

  • Womb Transplant UK

    lead OTHER

Principal Investigators

  • Richard Smith, FRCOG, MD · Imperial NHS Healthcare Trust

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
36 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-01-31
Primary Completion
2020-01-31
Completion
2020-01-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02388802 on ClinicalTrials.gov