Infertility is a disease of the reproductive system defined by failure to achieve pregnancy after prolonged periods of regular unprotected intercourse. It affects both male and female reproductive health and can result from diverse endocrine, anatomical, genetic, infectious, and age-related factors. The condition has major psychosocial and economic impacts.
New research shows that many people with disease-causing gene mutations never develop illness, challenging traditional assumptions. Studies of 'modifier genes' and genetic outliers are revealing how some individuals stay healthy, potentially leading to new treatments for genetic diseases.
The American Cancer Society's 2026 statistics show a historic 70% 5-year relative survival rate for all cancers, up from 49% in the mid-1970s. Progress is attributed to earlier detection, targeted therapies, and immunotherapies, though disparities persist for American Indian and Alaska Native populations.
Two studies reveal how 3D genome architecture shapes early human development. One shows enhancers pre-connect with future target genes before activation, while the other finds germ cells restructure chromosomes before meiosis — a step critical for lab-grown sperm and eggs.
Merck Foundation celebrated International Women's Day 2026 and hosted the 12th Africa Asia Luminary with African First Ladies, citing over 2,500 medical scholarships and 1,200 schoolgirl scholarships across Africa and Asia.
A meta-analysis of 20,806 cancer patients shows women have significantly improved survival rates but higher risk of severe treatment side effects compared to men. Separate research indicates nutrition counseling could support fertility in female cancer survivors, though implementation faces barriers. Specialized cancer nurses play a crucial role in providing stability and support throughout cancer treatment.
Analysis shows around a third of 54 drugs on TrumpRx.gov are cheaper in the UK, while the platform offers significant savings primarily for obesity and fertility drugs not typically covered by insurance.
The Trump administration launched TrumpRx on Feb. 5, a prescription drug website that displays discounted prices on 43 brand-name medications for out-of-pocket purchasers without insurance coverage.
Women with endometriosis face increased long-term risk for thyroid disorders including hypothyroidism and Graves disease, according to a 20-year retrospective study. ACOG released new clinical guidance aimed at reducing diagnostic delays through clinical diagnosis and earlier treatment initiation.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07773337 |
Ovarian Stromal Stiffness and Ovarian Reserve Parameters Via Transvaginal Shear Wave Elastography |
NOT_YET_RECRUITING | NA |
| NCT07771283 |
Purpose to Evaluate the Effectiveness of the Superovulation Stimulation Protocol Using Human Chorionic Gonadotropin (hCG) by Demonstrating Its Equivalence to Standard Controlled Ovarian Stimulation Protocols in Terms of Oocytes Retrieved, Blastulation While Maintaining an Economic Advantage |
ENROLLING_BY_INVITATION | NA |
| NCT07738068 |
Progesterone Luteal Support in Unexplained Infertility Management |
NOT_YET_RECRUITING | PHASE3 |
| NCT07736859 |
Satisfaction of Hysterosalpingo-Foam Sonography |
ENROLLING_BY_INVITATION | |
| NCT07725458 |
Patient Empowerment Project (PEP) Study |
NOT_YET_RECRUITING | |
| NCT07696351 |
Ultra-Long GnRH-a Pretreatment for FET Outcomes in Patients With Deep Infiltrating Endometriosis |
RECRUITING | PHASE4 |
| NCT07691073 |
Embryo QUAlity in Ovarian Stimulation With hMG. |
NOT_YET_RECRUITING | PHASE4 |
| NCT07684963 |
Effect of Varicocelectomy on Spermatogenic Cell Count and Semen Parameters |
NOT_YET_RECRUITING | NA |
| NCT07675213 |
Endometrial Peristalsis and Pregnancy Outcomes in Hormone Replacement Therapy (HRT) - Frozen Embryo Transfer (FET) Cycles |
RECRUITING | |
| NCT07666243 |
Outcomes of Embryos Created From Abnormally Fertilized Oocytes |
NOT_YET_RECRUITING |
