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Endometrial Local Injury and Implantation Failure

NCT00837733 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 115

Last updated 2009-02-05

No results posted yet for this study

Summary

The purpose of this study is to evaluate the influence of endometrial biopsy on increasing implantation rate in patients with recurrent implantation failures, 93 women with at least two implantation failures were evaluated. In case group endometrial biopsy was obtained from 48 patients in the luteal phase of previous cycle and implantation and clinical pregnancy rate were compared with 45 patients in control group. The results suggest that in vitro fertilization or intracytoplasmic sperm injection after endometrial biopsy increase pregnancy outcome.

Conditions

Interventions

PROCEDURE

Endometrial biopsy

Endometrial biopsy was done at luteal phase on the day 21-26 of spontaneous menstrual cycles, when GnRH agonist uses begun. Endometrial samples were taken by a biopsy catheter

PROCEDURE

Endometrial Biopsy

Biopsy catheter

Sponsors & Collaborators

  • Yazd Medical University

    collaborator OTHER

  • Yazd Research & Clinical Center for Infertility

    lead OTHER

Principal Investigators

  • Mohammad Ali Karimzadeh, Professor · Research and Clinical Center for Infertility

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
15 Years
Max Age
39 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-01-31
Primary Completion
2008-11-30
Completion
2008-12-31

Countries

  • Iran

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00837733 on ClinicalTrials.gov