MedTrace Logo

Role of Cardiometabolic Risk Factors in Childhood Bone Development

NCT02355717 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 400

Last updated 2019-11-20

No results posted yet for this study

Summary

The proposed research brings together complementary expertise to systematically elucidate the longitudinal effects of (1) total and regional body fat and (2) the metabolic impairment that accompanies obesity on bone development during growth. The contribution of this research will be significant because it will provide a solid foundation for understanding the influence of fat (total and regional distribution) on overall bone strength, and whether insulin resistance, beta-cell dysfunction, abnormal lipids, and inflammation could be underpinning factors in the fat-bone strength relationship via effects on bone modeling activity. This knowledge will provide critical information needed to maximize potential therapeutic interventions to counter the linked risks of obesity and osteoporosis, both major public health concerns.

Conditions

Interventions

OTHER

Observational Study

Sponsors & Collaborators

  • Augusta University

    lead OTHER

Principal Investigators

  • Norman K Pollock, Ph.D. · Department of Medicine, Medical College of Georgia, Augusta University

Eligibility

Min Age
9 Years
Max Age
15 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-12-31
Primary Completion
2021-12-01
Completion
2021-12-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02355717 on ClinicalTrials.gov