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CT-Based Changes in Bone and Marrow Among Patients on Oral Steroids

NCT04518722 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 2

Last updated 2026-04-07

No results posted yet for this study

Summary

The goal of this study is to assess the feasibility of emerging CT-based tools to measure changes in central and peripheral bone density, micro-structure, and marrow adipose tissue (MAT) among patients treated with oral steroids.

Conditions

  • Asthma
  • Bone Density, Low
  • Oral Steroid-Dependent Asthma (Disorder)

Interventions

RADIATION

CT Scan

Dual-energy mid-tibia CT, high-resolution single energy MDCT imaging of the distal tibia (ankle), and low radiation hip CT scans

RADIATION

DXA Scan

Basic DXA scans will be performed to measure areal BMD and body composition measures at the whole body, spine, and hip

OTHER

Steroid Intake Questionnaire

Questionnaire designed to quantify lifetime oral glucocorticoid intake

Sponsors & Collaborators

  • University of Iowa

    lead OTHER

Principal Investigators

  • Punam K Saha, PhD · University of Iowa

Eligibility

Min Age
25 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-12-01
Primary Completion
2021-09-28
Completion
2021-09-28

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04518722 on ClinicalTrials.gov