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The Impact of Glomerular Disorders on Bone Quality and Strength

NCT04528446 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 270

Last updated 2024-07-01

No results posted yet for this study

Summary

The primary objectives of this study are to: (1) determine the impact of glomerular disease on bone strength and (2) investigate the pathophysiologic underpinnings of impaired bone strength in glomerular disease.

Conditions

  • Glomerular Disease
  • Bone Diseases, Metabolic
  • Bone Fracture

Interventions

RADIATION

Dual-energy X-ray absorptiometry

DXA whole body, hip, spine, and radius at baseline, and 12-month visit.

RADIATION

High Resolution Peripheral Quantitative Computed Tomography (HR-pQCT)

HR-pQCT of the radius and tibia at baseline, and 12-month visit.

OTHER

Blood draw and Urine collection

The blood draw can be completed +/- 3 weeks from baseline or 12-month visit.

OTHER

Questionnaires

Questionnaires regarding fracture history, physical activity and dietary intake at baseline, and 12-month visit.

Sponsors & Collaborators

  • National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

    collaborator NIH

  • Columbia University

    lead OTHER

Principal Investigators

  • Thomas L. Nickolas, MD · Columbia University

Eligibility

Min Age
5 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-06-14
Primary Completion
2024-12-31
Completion
2024-12-31

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04528446 on ClinicalTrials.gov