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An fMRI Study on Temporal Discounting in Bipolar Disorder

NCT02323763 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 28

Last updated 2017-02-09

No results posted yet for this study

Summary

The investigators propose to explore the link between bipolar disorder, anxiety, and suicide by investigating intertemporal discounting in depressed, suicidal patients with bipolar I and II disorder who have various levels of anxiety. The investigators will determine the effect of anxiety on their intertemporal discounting (small rewards now compared to larger rewards later) in a decision-making paradigm and investigate the associated functional neuroanatomy using functional magnetic resonance imaging (fMRI).

Conditions

Interventions

OTHER

fMRI Scanning

Imaging will be performed on a 3T Siemens Trio scanner. Each MRI scanning session will last no more than 90 minutes. fMRI will be used to determine brain activation and differences in intertemporal discounting.

Sponsors & Collaborators

  • American Foundation for Suicide Prevention

    collaborator OTHER

  • Massachusetts General Hospital

    lead OTHER

Principal Investigators

  • Andrew A. Nierenberg, M.D. · Massachusetts General Hospital

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-07-14
Primary Completion
2016-08-29
Completion
2016-08-29

Countries

  • United States

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02323763 on ClinicalTrials.gov