Rostral Dorsal Cingulum Bundle Connectivity in Patients With Bipolar Disorder

NCT02655978 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 45

Last updated 2020-11-12

No results posted yet for this study

Summary

The overall goal of this study is to employ diffusion-weighted imaging (DWI) and tractography to investigate differences in connectivity in the rostral dorsal cingulum bundle (CB) in patients with bipolar disorder type I (BDI) or bipolar type II (BDII) compared to matched controls, and to utilize this information to determine if high-frequency deep brain stimulation (DBS) of the rostral dorsal CB has realistic potential as a therapy for producing mood stabilization in patients with BDI or BDII.

Conditions

Interventions

OTHER

Magnetic Resonance Imaging

Sponsors & Collaborators

  • National Institutes of Health (NIH)

    collaborator NIH
  • University Hospitals Cleveland Medical Center

    lead OTHER

Principal Investigators

  • Jennifer A Sweet, MD · University Hospitals Cleveland Medical Center

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-01-31
Primary Completion
2019-10-31
Completion
2019-10-31

Countries

  • United States

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02655978 on ClinicalTrials.gov