Most advanced cancer patients misunderstand whether their treatment is curative. Honest prognosis discussions improve outcomes without worsening distress, while diagnostic delays persist; pathologist involvement can speed treatment.
NRx said the FDA outlined a path for a New Drug Application for NRX-100, a preservative-free ketamine formulation for depression with suicidality. The company plans to submit the NDA by June 2026 and said no additional nonclinical or bridging studies would be required.
Recent studies reveal AI chatbots face significant challenges in medical applications, with one study showing ChatGPT Health under-triaged 51.6% of emergency cases. Cancer patients using an AI chatbot experienced 22% withdrawal rates due to usability issues, while medical researchers show cautious adoption with 40.3% reporting AI use in research.
Bunnie Xo, wife of country star Jelly Roll, revealed she experienced suicidal thoughts while taking semaglutide, describing December 2025 as "one of the darkest times of my life." She emphasized the importance of discussing mental health side effects of weight-loss medications and encouraged others facing similar struggles to seek help.
Compass Pathways reports positive Phase 3 results for synthetic psilocybin in treatment-resistant depression, while a Phase 2 trial demonstrates rapid antidepressant effects from single-dose DMT. Both studies show modest efficacy signals amid growing pharmaceutical interest in psychedelic compounds.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07783490 |
Suicide Safety Planning |
NOT_YET_RECRUITING | NA |
| NCT07780084 |
Stratified Care Intervention for Suicidal Ideation, Depression, and Non-Suicidal Self-Injury in Adolescents (Reframe-IT+ & CARIBOU) |
ACTIVE_NOT_RECRUITING | NA |
| NCT07767604 |
Effectiveness of the MindBridge Mobile Health Module for Young Adults at Risk of Suicide |
NOT_YET_RECRUITING | NA |
| NCT07762612 |
"Gwan Enjoy Life:" A Peer-Supported Mental Health Mentoring Intervention to Improve Engagement in Care Among Sexual Minority Men Living With HIV in Jamaica |
NOT_YET_RECRUITING | NA |
| NCT07756567 |
Developing a Recovery-Oriented Suicide Prevention Program for Young People at Clinical High Risk for Psychosis |
NOT_YET_RECRUITING | NA |
| NCT07719816 |
Qualitative Study of Student Financial Insecurity and Psychiatry |
NOT_YET_RECRUITING | |
| NCT07717866 |
Trifecta Research Study |
ACTIVE_NOT_RECRUITING | |
| NCT07712796 |
Empowerment Self Defense Program for Adult Native Women Survivors of Sexual Violence |
NOT_YET_RECRUITING | NA |
| NCT07661901 |
Reward Sensitivity Digital Intervention for Suicide Risk |
RECRUITING | NA |
| NCT07654127 |
User Evaluation Think Life |
NOT_YET_RECRUITING |
