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Neurofeedback to Reduce Spontaneous Recovery of Threat Expectancy

NCT07122739 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2026-02-23

No results posted yet for this study

Summary

This study tests the efficacy of a new behavioral intervention with the goal of reducing spontaneous recovery of threat expectancy in healthy adults. This real-time functional magnetic resonance imaging (fMRI) neurofeedback intervention delivers feedback based on a functional connection between the prefrontal cortex and the hippocampus.

Conditions

  • Healthy

Interventions

BEHAVIORAL

Active Real-time fMRI Neurofeedback

Active neurofeedback to target a functional connection associated with increased memory control ability

BEHAVIORAL

Sham Real-time fMRI neurofeedback

Sham neurofeedback

Sponsors & Collaborators

  • National Institute of Mental Health (NIMH)

    collaborator NIH

  • Trustees of Princeton University

    lead OTHER

Principal Investigators

  • Kenneth A. Norman, Ph.D. · Princeton University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-07-17
Primary Completion
2027-12-31
Completion
2028-06-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07122739 on ClinicalTrials.gov