Safety and Efficacy of Maintenance of Etomidate in General Anesthesia
NCT05223907 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 1080
Last updated 2024-06-05
Summary
This study was designed to use etomidate combined with sevoflurane intravenously to maintain anesthesia process under the monitoring of BIS. Propofol was used as the controls. Blood pressure and heart rate were recorded during operation. The VAS pain score was observed after surgery.To investigate whether this program can better maintain intraoperative hemodynamic stability, improve the quality of recovery, and reduce the incidence of postoperative adverse reactions.
Conditions
- General Anesthesia
Interventions
- DRUG
-
Etomidate
Etomidate will be used for general anesthesia
- DRUG
-
Propofol
Propofol will be used for general anesthesia
Sponsors & Collaborators
-
Henan Provincial People's Hospital
lead OTHER
Principal Investigators
-
Jiaqiang Zhang, PHD · Henan Provincial People's Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-05-01
- Primary Completion
- 2022-12-31
- Completion
- 2022-12-31
Countries
- China
Study Locations
More Related Trials
-
Impact of Anesthesia Maintenance Methods on Long-term Survival
NCT02660411 ·Status: COMPLETED ·Phase: NA
-
Relationship Between Remimazolam and Etomidate in Induction of General Anesthesia
NCT07012902 ·Status: NOT_YET_RECRUITING ·Phase: EARLY_PHASE1
-
Comparison of Propofol and Sevoflurane as Maintaining Anesthetics During General Anesthesia of Cesarean Section
NCT03149588 ·Status: UNKNOWN ·Phase: PHASE4
-
Target Controlled Infusion of Etomidate or Propofol for Anesthesia of Thoracoscopic Mitral Valve Replacement Surgery
NCT02644980 ·Status: UNKNOWN ·Phase: PHASE4
-
General Anesthetic Mode and Postoperative Complications
NCT03335579 ·Status: TERMINATED
-
Effects of Intravenous Anesthesia and Balanced Anesthesia on Flash Visual Evoked Potentials
NCT04725032 ·Status: RECRUITING ·Phase: NA
-
Evaluation of Equivalent Minimum Alveolar Concentration (eMAC) During Propofol/Remifentanil Anesthesia
NCT05789992 ·Status: COMPLETED ·Phase: NA
-
Comparison of Postoperative Recovery of Sevoflurane and Propofol After Transsphenoidal Surgery
NCT05822817 ·Status: COMPLETED ·Phase: PHASE4
-
Study on Opioid-free Anesthesia Protocol With S-ketamine and Propofol
NCT05242081 ·Status: UNKNOWN ·Phase: NA
-
A Trial to Evaluate the Efficacy and Safety of Methoxyetomidate Hydrochloride for Injection (ET-26) for the Induction of General Anesthesia in Elective Surgery Subjects
NCT06203431 ·Status: RECRUITING ·Phase: PHASE3
-
Dual-loop Target Controlled Infusion for Coadministration of Propofol and Remifentanil Guided by Narcotrend Index
NCT02890186 ·Status: UNKNOWN ·Phase: PHASE4
-
Analysis of Autonomic Function During Anesthesia Using Response Surface Model
NCT03072069 ·Status: COMPLETED
-
Comparison of Anesthesia Effects of Sevoflurane and Propofol Combined With Dexmedetomidine in Intraoperative Neuromonitoring During Thyroidectomy
NCT04680650 ·Status: UNKNOWN ·Phase: NA
-
Bispectral Index Guiding Etomidate Used in Children Aged 3 to 10 for Clinical Anesthesia Induction
NCT02182648 ·Status: UNKNOWN ·Phase: PHASE4
-
Impact of Anesthesia Maintenance Methods on 5-year Survival After Surgery
NCT05343260 ·Status: COMPLETED ·Phase: NA
-
The Effect of Propofol or Etomidate on Cognitive Function for 1-3 Years Old Children
NCT02199990 ·Status: UNKNOWN
-
Observation of Propofol Titration at Different Speeds
NCT04595591 ·Status: COMPLETED ·Phase: NA
-
The Effect of Anesthetics on Oxidative Stress and Apoptosis Status in Children
NCT02711280 ·Status: COMPLETED ·Phase: NA
-
The Effect of Thoracic Epidural Anesthesia With Different Block Level on Propofol Induction
NCT02135016 ·Status: COMPLETED ·Phase: PHASE4
-
A Comparison of the Effects of Intraoperative Administration of Metoprolol or Esmolol on General Anesthetic Requirement
NCT00756236 ·Status: COMPLETED ·Phase: NA
-
The Effects of Spinal Anesthesia on ED50 and BIS50 of Etomidate for the Loss of Consciousness
NCT03240055 ·Status: COMPLETED ·Phase: NA
-
Efficacy and Safety Study of Two Propofol Formulations
NCT00506246 ·Status: COMPLETED ·Phase: PHASE3
-
Impact of Etomidate vs. Propofol on Infectious Complications Post Cardiac Surgery
NCT04281706 ·Status: COMPLETED
-
Difference Between Inhalation Anesthesia and Total Intravenous Anesthesia in Free Flap Surgery
NCT03263078 ·Status: COMPLETED ·Phase: NA
-
The Effect of General Anesthesia with Remimazolam and Propofol on Rhythmic State and Cognitive Function
NCT06775366 ·Status: NOT_YET_RECRUITING ·Phase: NA