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Negative Work Exercise for the Treatment of Knee Arthritis

NCT02098096 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 54

Last updated 2018-09-20

No results posted yet for this study

Summary

The purpose of this study is to develop a negative work exercise regimen as an intervention for posttraumatic osteoarthritis (PTOA). "Negative work" is the force produced by muscles as they lengthen, and regularly occurs with common activities such as lowering an object from a shelf or walking down stairs. In this study, the investigators are examining the effectiveness of negative work exercise over a 12-week period in older, male, Veterans.

Conditions

Interventions

OTHER

Negative Work

Exercise will be performed twice per week for 12 weeks and exercise intensity will be progressed in three phases. These phases are: 1. Familiarization 2. Acclimatization 3. Progression Exercise volume will be 3 sets of 10 repetitions (progressing to 4 sets at Week 6) for the knee flexors and extensors. All exercise will be supervised by a physical therapist and performed on a Biodex isokinetic dynamometer.

OTHER

Stretching

Home exercise program will be performed by the Placebo Comparator group and feature stretching over the 12 week intervention period.

Sponsors & Collaborators

Principal Investigators

  • Michael Harris-Love, DSc · Washington DC VA Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
50 Years
Max Age
70 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-03-31
Primary Completion
2017-10-31
Completion
2019-11-30

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02098096 on ClinicalTrials.gov