Mechanisms of Refractory Hypertension (Carvedilol)
NCT02357004 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL
Last updated 2020-06-12
Summary
The purpose of this protocol is test whether patients with hypertension refractory to antihypertensive treatment have evidence of excessive sympathetic (i.e., nervous system) activity.
Conditions
- Hypertensive
Interventions
- DRUG
-
Carvedilol
CR 40 mg daily in addition to normal BP medications
- DRUG
-
Chlorthalidone
12.5 mg daily in addition to normal BP medications
Sponsors & Collaborators
-
University of Alabama at Birmingham
lead OTHER
Principal Investigators
-
David A. Calhoun, MD · Cardiology Department - University of Alabama at Birmingham
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 19 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-02-28
- Primary Completion
- 2020-01-31
- Completion
- 2020-01-31
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