BNP Pharmacodynamics and Effects on Metabolism in Lean and Obese Subjects
NCT01977859 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 4
Last updated 2018-02-14
Summary
The purpose of this study is to collect data to help researchers better understand the various causes of obesity, which may lead to the development of new obesity treatment options.
Conditions
Interventions
- DRUG
-
Nesiritide
- DRUG
-
Saline
Sponsors & Collaborators
-
Sanford-Burnham Medical Research Institute
collaborator OTHER -
AdventHealth Translational Research Institute
lead OTHER
Principal Investigators
-
Richard E. Pratley, MD · AdventHealth
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2013-11-30
- Primary Completion
- 2016-02-15
- Completion
- 2017-02-28
Countries
- United States
Study Locations
More Related Trials
-
The Belly Fat Study: Nutritional Intervention to Improve Metabolic Health in Subjects With Increased Abdominal Adiposity
NCT02194504 ·Status: COMPLETED ·Phase: NA
-
Breathing & Blood Pressure
NCT05632406 ·Status: RECRUITING
-
Energy Metabolism and Nutrient Absorption in Lean and Obese Individuals
NCT00414063 ·Status: COMPLETED
-
Effects of Weight Loss on Vascular Function in Obese Subjects
NCT04198519 ·Status: UNKNOWN ·Phase: NA
-
The Role of Atrial Natriuretic Peptide in the Lipolytic Process: Effect of Obesity and Exercise
NCT02418728 ·Status: COMPLETED
-
Effect of Weight Loss on Myocardial Metabolism and Cardiac Relaxation in Obese Adults
NCT00572624 ·Status: COMPLETED ·Phase: NA
-
Leptin in the Maintenance of Reduced Body Weight
NCT01155180 ·Status: COMPLETED ·Phase: PHASE2
-
Sympathetic Transduction in Obesity
NCT05590546 ·Status: NOT_YET_RECRUITING
-
Relative Sarcopenia and Cardiometabolic Risk in Young Adults With Obesity
NCT04195061 ·Status: COMPLETED
-
Effect of PDE5 Inhibition on Adipose Metabolism in Humans
NCT04684589 ·Status: COMPLETED ·Phase: PHASE2
-
A Cross-sectional Study Examining Adipose Tissue in Obstructive Sleep Apnea
NCT03307330 ·Status: RECRUITING
-
Evaluation of the Effectiveness of a Comprehensive Visceral Adiposity-Focused Anti-Obesity Program
NCT04807959 ·Status: COMPLETED
-
Weight Loss in Diabetic, Older Obese Adults
NCT00108329 ·Status: COMPLETED ·Phase: NA
-
Molecular, Cellular, and Genetic Characterization of Human Adipose Tissue and Its Role in Metabolism
NCT02692885 ·Status: RECRUITING
-
The Weight of Cardiovascular Disease
NCT06053645 ·Status: RECRUITING
-
Fat Gain and Cardiovascular Disease Mechanisms
NCT00589498 ·Status: COMPLETED ·Phase: PHASE3
-
The "Metabolically-obese Normal-weight" Phenotype and Its Reversal by Calorie Restriction
NCT03239782 ·Status: COMPLETED ·Phase: NA
-
Effect of Oral Feeding on Gastric Emptying, Gut Blood Flow, and Hormone Responses in Obese and Healthy Weight Subjects
NCT03860623 ·Status: COMPLETED
-
Obesity Paradox in Non Valvular Atrial Fibrillation Regarding Outcomes: Fact or Fiction
NCT03904329 ·Status: UNKNOWN
-
Fat Tissue Microperfusion to Measure Leptin Secretion and Its Relations With Fat Breakdown in Humans
NCT00001722 ·Status: COMPLETED
-
Physiologic Plasticity of Intramyocardial Lipid Storage
NCT01921075 ·Status: COMPLETED
-
Obesity Phenotypes and Its Relation to Cardiovascular Diseases
NCT06092021 ·Status: NOT_YET_RECRUITING
-
Re-energize With Nutrition, Exercise and Weight Loss
NCT00712127 ·Status: COMPLETED ·Phase: NA
-
Breaking Sitting and Metabolic Health in Sedentary Lean Adults
NCT05306613 ·Status: COMPLETED ·Phase: NA
-
The Role of Brown Adipose Tissue in Triglyceride Clearance in People
NCT02786251 ·Status: COMPLETED ·Phase: NA