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Effects of Change in Insulin Resistance and Systemic Inflammation on Brain Structure and Function

NCT03215888 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 29

Last updated 2021-07-02

No results posted yet for this study

Summary

Obesity is associated with alterations in brain structure and cognitive impairment and is a risk factor for Alzheimer's disease and vascular dementia. The mechanisms underlying obesity related decline in cognitive function are not fully understood. The long-term goal of this project is to understand how obesity affects cognitive function, with the aim to develop new ways to prevent and treat obesity related cognitive decline

Conditions

  • Obesity
  • Bariatric Surgery Candidate

Interventions

PROCEDURE

bariatric surgery

Obese patients will undergo brain imaging, neurocognitive function testing and measurement of insulin resistance and inflammatory markers pre- and post bariatric surgery

Sponsors & Collaborators

Principal Investigators

  • Amir Moheet · University of Minnesota

Eligibility

Min Age
30 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-11-01
Primary Completion
2020-02-11
Completion
2020-02-11

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03215888 on ClinicalTrials.gov