CPAP and Nebivolol in Hypertensive Obstructive Sleep Apnea (OSA) Patients.
NCT01771406 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 36
Last updated 2013-01-18
Summary
The aim of this study is to examine how effective CPAP treatment and treatment with nebivolol are respectively on reducing blood pressure and on endothelial dysfunction in patients suffering from obstructive sleep apnea and hypertension.
Conditions
- Hypertension
- Endothelial Dysfunction
- Obstructive Sleep Apnea
Interventions
- DRUG
-
Nebivolol
8 weeks of Nebivolol treatment (5mg/day)
- DEVICE
-
Continuous positive airway pressure (CPAP)
8 weeks of CPAP treatment
Sponsors & Collaborators
-
Universitaire Ziekenhuizen KU Leuven
lead OTHER
Principal Investigators
-
Catharina Belge, M.D., Ph.D. · Universitaire Ziekenhuizen KU Leuven
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-02-28
- Primary Completion
- 2016-02-29
- Completion
- 2016-02-29
Countries
- Belgium
Study Locations
More Related Trials
-
Oxidative Stress and Endothelial Dysfunction in Obstructive Sleep Apnea
NCT00646971 ·Status: TERMINATED ·Phase: NA
-
Central and Peripheral Blood Pressure in Treatment of Obstructive Sleep Apnea.
NCT02078778 ·Status: UNKNOWN ·Phase: NA
-
Mechanisms for Individual Differences in Hypertension in Obstructive Sleep
NCT03176732 ·Status: COMPLETED
-
Effects of Suboptimal CPAP Therapy on Symptoms of Obstructive Sleep Apnoea
NCT02781740 ·Status: COMPLETED ·Phase: NA
-
Cardiovascular Phenotype Study in Patients With Obstructive Sleep Apnea Syndrome
NCT00764218 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Vasoactive Hormones During the Night in Patients With Obstructive Sleep Apnea Before and After Treatment With CPAP.
NCT00360659 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of CPAP Therapy on Blood Pressure and Heart Rate Variability in Obstructive Sleep Apnea
NCT04712656 ·Status: RECRUITING
-
Sibutramine Versus Continuous Positive Airway Pressure (CPAP)in Obstructive Sleep Apnea (OSA) Patients
NCT00729963 ·Status: COMPLETED ·Phase: PHASE4
-
The Effects of Obstructive Sleep Apnea and Its Intervention on Coronary Heart Disease
NCT02059993 ·Status: COMPLETED ·Phase: NA
-
Personalised Treatment for OSA
NCT06915077 ·Status: ENROLLING_BY_INVITATION
-
Effect of Continuous Positive Airway Pressure (CPAP) on Hypertension and Cardiovascular Morbidity-Mortality in Patients With Sleep Apnea and no Daytime Sleepiness
NCT00127348 ·Status: COMPLETED ·Phase: PHASE4
-
Obstructive Sleep Apnea (OSA), Hypertension , β1 Subunit of Maxi-k+ Channel and Cardiovascular Risk
NCT01791270 ·Status: COMPLETED
-
Masked Hypertensive Patients With Obstructive Sleep Apnea
NCT04251975 ·Status: COMPLETED ·Phase: NA
-
Minimally Invasive Detection of a Sleep Apnoea
NCT03760159 ·Status: TERMINATED
-
Cardiovascular Impact of Obstructive Sleep Apnea Treatment in Normotensive Patients
NCT00741520 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of CPAP on Blood Pressure in Patients With Sleep Apnea and Refractory Hypertension
NCT00863135 ·Status: COMPLETED ·Phase: NA
-
Efficacy of CPAP Treatment on Blood Pressure of Resistant Hypertension Patients With Obstructive Sleep Apnea Syndrome
NCT01508754 ·Status: COMPLETED ·Phase: PHASE4
-
Improving 24-hour Blood Pressure in Obstructive Sleep Apnea
NCT04021550 ·Status: WITHDRAWN ·Phase: EARLY_PHASE1
-
Effect of Continuous Positive Airway Pressure (CPAP) Treatment in the Control of Refractory Hypertension
NCT00616265 ·Status: COMPLETED ·Phase: NA
-
Antihypertensive Effect of Continuous Positive Airway Pressure in Resistant Hypertensive Patients With Sleep Apnea
NCT00929175 ·Status: COMPLETED ·Phase: PHASE4
-
Clinical Outcomes of Continuous Positive Airway Pressure Treatment in People With Obstructive Sleep Apnea and Chronic Pain
NCT06834724 ·Status: RECRUITING
-
Effects of CPAP on Diet, Physical Activity, and Cardiovascular Risk
NCT01944020 ·Status: COMPLETED ·Phase: NA
-
Effect of Continuous Positive Airway Pressure (CPAP) Therapy on Changes of Blood Pressure Between Day and Night
NCT01865864 ·Status: TERMINATED
-
The Effects of Continuous Positive Airway Pressure (CPAP) on Sympathetic Activity in Different Sites of Activation
NCT01336335 ·Status: UNKNOWN ·Phase: PHASE3
-
Role of Sleep Apnea and Sympathetic Activity in Resistant Hypertensive Patients.
NCT01875341 ·Status: COMPLETED ·Phase: PHASE3