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Sleep Apnea and Refractory Hypertension: Prevalence and Effect of CPAP Treatment

NCT00459914 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 130

Last updated 2009-01-29

No results posted yet for this study

Summary

A small number of uncontrolled studies have shown a high prevalence of sleep apnea in patients with refractory hypertension and that CPAP treatment achieves a significant reduction of blood pressure in the short term.

The purpose of this study is to assess the prevalence of sleep apnea in patients with refractory hypertension, and the effects of continuous positive pressure treatment on systemic blood pressure and on serum markers of endothelial dysfunction and angiogenesis.

Conditions

Interventions

DEVICE

cpap treatment during sleep

CPAP

Sponsors & Collaborators

  • Fundacio Catalana de Pneumologia

    lead OTHER

Principal Investigators

  • Lourdes Lozano, MD · Hospital General Universitari Vall d'Hebron

  • Jose Luis Tovar, MD · Hospital General Universitari Vall d'Hebron

  • Gabriel Sampol, MD · Hospital General Universitari Vall d'Hebron

  • Odile Romero, MD · Hospital General Universitari Vall d'Hebron

  • Pilar Chacon, MD · Hospital General Universitari Vall d'Hebron

  • Jose Rios · Universitat Autonoma de Barcelona

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-01-31
Primary Completion
2008-05-31
Completion
2008-12-31

Countries

  • Spain

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00459914 on ClinicalTrials.gov