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Change in Airway Responsiveness After Allergen Exposure

NCT01699594 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 11

Last updated 2015-04-09

No results posted yet for this study

Summary

Exposure to allergens changes the way the airway responds to some stimuli (methacholine). The investigators will look at whether or not exposure to allergens changes the way the airway responds to a different stimuli (mannitol) and compare that with the known stimuli (methacholine).

Conditions

  • Allergic Asthma

Interventions

DRUG

Mannitol

Indirect bronchoprovocation agent being compared to direct bronchoprovocation agent (methacholine)

DRUG

Methacholine Chloride

Direct bronchoprovocation agent being compared to indirect bronchoprovocation agent (mannitol)

Sponsors & Collaborators

  • University of Saskatchewan

    lead OTHER

Principal Investigators

  • Donald W Cockcroft, MD · University of Saskatchewan

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-10-31
Primary Completion
2014-05-31
Completion
2014-05-31

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01699594 on ClinicalTrials.gov