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Effects of Allergen Inhalation on Adenosine Receptor Expression in Sputum and Peripheral Blood

NCT00116311 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2007-03-21

No results posted yet for this study

Summary

The purpose of this study is to determine whether asthmatics have different adenosine receptor expression profiles than healthy controls. We hypothesize that asthmatics will have increased adenosine receptor expression versus control subjects.

We also want to study the effects of allergen inhalation on adenosine receptor expression in asthmatics. We believe that adenosine receptor expression will be upregulated after allergen inhalation.

Both hypotheses are being tested in sputum and peripheral blood.

Conditions

Interventions

BEHAVIORAL

allergen inhalation

BEHAVIORAL

withdrawal of medication

PROCEDURE

sputum induction

Sponsors & Collaborators

  • Groningen Research Institute for Asthma and COPD

    lead OTHER

Principal Investigators

  • Dirkje S Postma, prof. MD PhD · University Medical Center Groningen, Department of Pulmonology, hanzeplein 1, 9713 GZ Groningen, The Netherlands

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2005-07-31
Completion
2007-02-28

Countries

  • Netherlands

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00116311 on ClinicalTrials.gov