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Effect of Noni Juice on Lipid Peroxidation-derived DNA Adducts in Heavy Smokers

NCT01677169 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 317

Last updated 2019-09-11

No results posted yet for this study

Summary

The purpose of this study was to determine if noni juice reduces lipid hydroperoxide (LOOH) and malondialdehyde (MDA) derived-DNA adducts, markers of oxidative DNA damage, in peripheral blood lymphocytes of cigarette smokers.

Conditions

  • DNA Damage

Interventions

DIETARY_SUPPLEMENT

Noni juice

Ingestion of noni juice, a source of iridoids, daily for 30 days.

DIETARY_SUPPLEMENT

Placebo

Sponsors & Collaborators

  • University of Illinois at Chicago

    collaborator OTHER

  • Tahitian Noni International, Inc.

    lead INDUSTRY

Principal Investigators

  • Mian-ying Wang, MD · University of Illinois at Chicago

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2000-09-30
Primary Completion
2005-11-30
Completion
2006-08-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01677169 on ClinicalTrials.gov