Pulse Wave Analysis and Velocity in Patients With Chronic Renal Failure: a Cross-sectional Observational Study to Assess Association With Left Ventricular Hypertrophy, Uremic Toxins and Inflammation.
NCT01579032 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 90
Last updated 2018-10-17
Summary
The aims of the presented study are as follows:
1. To evaluate the endothelial function and arterial stiffness in a large cohort of prevalent CKD patients by means of non-invasive applantion tonometry.
2. To evaluate the association between the serum levels of the representatives of the various classes of uremic toxins and markers of endothelial function and arterial stiffness.
3. To evaluate the association between markers of inflammation and oxidative stress and markers of endothelial function and arterial stiffness.
4. To evaluate the association between echocardiographic parameters and markers of arterial stiffness
Conditions
- Arterial Stiffness
- CHRONIC RENAL FAILURE
- Left Ventricular Hypertrophy
Sponsors & Collaborators
-
Universitaire Ziekenhuizen KU Leuven
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2004-01-31
- Primary Completion
- 2012-01-31
- Completion
- 2012-01-31
Countries
- Belgium
Study Locations
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