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Assessment of Longitudinal Changes in Endothelial Function and Oxidative Stress in Normotensive Patients With ADPKD

NCT03493802 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 18

Last updated 2024-05-06

No results posted yet for this study

Summary

The purpose of this study is to determine whether patients with autosomal dominant polycystic kidney disease (ADPKD) present with abnormal endothelial function, increased levels of NOX4 activity and mitochondrial abnormalities, contributing to oxidative stress from early stages that correlate with disease severity.

Conditions

  • Autosomal Dominant Polycystic Kidney Disease

Sponsors & Collaborators

  • University of Kansas Medical Center

    collaborator OTHER

  • Mayo Clinic

    lead OTHER

Principal Investigators

  • Maria V Irazabal, M.D., Ph.D. · Mayo Translational PKD Center, Mayo Clinic

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-11-01
Primary Completion
2020-01-17
Completion
2020-01-17

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03493802 on ClinicalTrials.gov