Arterial Stiffness, Wave Reflections and Renal Failure
NCT00354588 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 115
Last updated 2010-11-04
Summary
1. Cardiovascular risk is high in patients with renal failure.
2. Cross-sectional studies have indicated a relationship between arterial stiffness and renal function. However, there are no prospective longitudinal studies in the literature.
3. In dialysis patients, arterial stiffness as well as wave reflections, predict mortality. However, there are no data on patients with mild-to-moderate renal impairment available.
4. Therefore, we designed a study to test the hypothesis that: a) measures of arterial stiffness and wave reflections predict the progression of renal impairment in patients with mild-to-moderate renal failure; and b) measures of arterial stiffness and wave reflections predict cardiovascular events in patients with mild-to-moderate renal failure
Conditions
- Chronic Renal Failure
- Arterial Stiffness
- Arterial Wave Reflections
Sponsors & Collaborators
-
Klinikum Wels-Grieskirchen
lead OTHER
Principal Investigators
-
Thomas Weber, MD · Cardiology Department, Klinikum Wels, Austria
-
Manfred Wallner, MD · Nephrology Department, Klinikum Wels, Austria
Eligibility
- Min Age
- 19 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-01-31
- Primary Completion
- 2010-10-31
- Completion
- 2010-10-31
Countries
- Austria
Study Locations
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