Assess the Effect of Treating Periodontal Disease on Cardiovascular Function in Young Adults
NCT01376791 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 92
Last updated 2013-04-23
Summary
We propose to examine a population of Native Americans who have had little or no dental care, and to determine if periodontal disease is associated with early signs of vascular dysfunction or systemic inflammation. We then propose to treat the periodontitis and re-evaluate vascular function. We will determine if gingivitis or mild/moderate periodontitis is associated with detectable vascular dysfunction. Microbial metagenomics will be correlated with vascular function.
Conditions
- Periodontal Disease
- Atherosclerosis
Sponsors & Collaborators
-
Indian Council of Medical Research
collaborator OTHER_GOV -
University of California, San Diego
collaborator OTHER -
San Diego State University
lead OTHER
Principal Investigators
-
Roberta A Gottlieb, MD · San Diego State University
Eligibility
- Min Age
- 21 Years
- Max Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2010-12-31
- Primary Completion
- 2012-12-31
- Completion
- 2012-12-31
Countries
- United States
Study Locations
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