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The Occurrence of Periopathogens in Betel-Nut Chewers and the Effects of Areca-Nut on Periopathogens

NCT00155571 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 186

Last updated 2005-11-28

No results posted yet for this study

Summary

Periodontal disease is considered to be an infection disease. Recent evidence supported the role of smoking as a potent risk factor for the development of periodontal disease. However, the effect of another oral habit, betel quid chewing on periodontal tissues has not been well determined. The purpose of the present study is to analysis the role of bacteria on the periodontium in the betel quid chewers. Plaque samples will be collected from betel quid chewers and the occurrence of periodotopathogens will be analyzed Since most chewers also smokers, plaque samples from age matched smokers but not betel chewers and non-smokers will analysis for comparison. An in vitro test is also performed to evaluate whether the extract has a direct inhibitory effect on common periodontal pathogens, such as Porphyromoans gingivalis, Bacteroides forsythus, Actinobacillus actinomycetemcomitans.

Conditions

  • Periodontitis

Sponsors & Collaborators

  • National Science and Technology Council, Taiwan

    collaborator OTHER_GOV

  • National Taiwan University Hospital

    lead OTHER

Principal Investigators

  • Man-ying Wang, DDS, MS · Department of Periodontics, National Taiwan University Hospital

Eligibility

Min Age
20 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2001-08-31

Countries

  • Taiwan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00155571 on ClinicalTrials.gov