MedTrace Logo

MR INFORM - MR Perfusion Imaging to Guide Management of Patients With Stable Coronary Artery Disease

NCT01236807 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 915

Last updated 2022-06-24

No results posted yet for this study

Summary

The purpose of this study is to determine if MR Perfusion Imaging is non-inferior to coronary angiography with measurement of Fractional Flow Reserve (FFR) in guiding management of patients with stable chest pain.

* All patients will undergo an MR Perfusion Imaging test.
* Further management will be guided by the result of the cardiac MRI in half of the patients (chosen by random).
* The other half will undergo coronary angiography with measurement of FFR. The result of this test alone will guide their further management. The result of the initial MR Perfusion test will not be available to the treating doctors of this group.
* All patients will receive optimal medical therapy (OMT)
* All patients will undergo follow-up to find out if they have any relevant heart related events.

Conditions

Interventions

PROCEDURE

MR perfusion guidance

Coronary revascularization guided by MR perfusion imaging

PROCEDURE

FFR guidance

Coronary revascularization guided by invasive angiography and FFR

Sponsors & Collaborators

Principal Investigators

  • Eike Nagel, MD, PhD · Goethe University Frankfurt

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-12-31
Primary Completion
2016-08-31
Completion
2016-12-31

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01236807 on ClinicalTrials.gov