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Clinical Evaluation of Magnetic Resonance Imaging in Coronary Heart Disease-2

NCT01664858 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 1202

Last updated 2018-11-23

Study results available
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Summary

CE-MARC 2 is a randomised controlled trial to determine diagnosis and patient management in patients presenting to outpatient clinics with suspected stable angina. Cardiac Magnetic Resonance Imaging (at 3Tesla) will be evaluated prospectively against current best clinical practice (defined by international guidelines). The study hypothesis is that 3Tesla CMR-guided management of patients with suspected stable angina is superior to current clinical practice based on 1) the principles of the National Institutes for Clinical Excellence (NICE) CG95 guidelines (2010); 2) SPECT AHA appropriateness criteria, in terms of avoiding study-defined unnecessary invasive coronary angiography.

Conditions

Interventions

OTHER

3T CMR

3Tesla Cardiac Magnetic Resonance Imaging

OTHER

SPECT

SPECT: Single Photon Emission Computed Tomography

OTHER

CT calcium score

CT calcium score

OTHER

CT coronary angiography

CT coronary angiography

OTHER

X-Ray coronary angiography

X-Ray coronary angiography

Sponsors & Collaborators

  • University of Leicester

    collaborator OTHER

  • University of Glasgow

    collaborator OTHER

  • British Heart Foundation

    collaborator OTHER

  • University of Leeds

    lead OTHER

Principal Investigators

  • John P Greenwood, PhD · University of Leeds

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
30 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-11-30
Primary Completion
2016-03-31
Completion
2018-03-31

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01664858 on ClinicalTrials.gov