Nutrigenomics Investigation of the Body's Metabolic Response to 2 Different Meal Challenges
NCT01172951 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 200
Last updated 2011-01-11
Summary
The purpose of this study is to investigate the biological response to a metabolic stress, given in the form of a high carbohydrate or fat meal in normal weight, overweight and obese individuals and to further explore these responses using novel metabolomic, proteomic, transcriptomic and genotyping techniques.
Conditions
- Healthy Subjects
Interventions
- OTHER
-
Oral glucose tolerance test
75g anhydrous glucose powder mixed with 100mls water
- OTHER
-
Oral lipid tolerance test
150ml drink composed of 2 commercially available high fat products
Sponsors & Collaborators
-
University College Dublin
lead OTHER
Principal Investigators
-
Michael J Gibney, PhD · University College Dublin
-
Donal O'Shea, MD · St Vincent's University Hospital, Ireland
-
Helen Roche, PhD · University College Dublin
-
Lorraine Brennan, PhD · University College Dublin
-
Eileen Gibney, PhD · University College Dublin
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2008-12-31
- Primary Completion
- 2010-12-31
- Completion
- 2010-12-31
Countries
- Ireland
Study Locations
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