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NOMOTHETICOS: Nonlinear Modelling of Thyroid Hormones' Effect on Thyrotropin Incretion in Confirmed Open-loop Situation

NCT01145040 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 138

Last updated 2020-10-08

No results posted yet for this study

Summary

The NOMOTHETICOS study is a unicentric cross-sectional study for a quantitative analysis of feedback-inhibition in the thyrotropic homeostatic control. Structural parameters are obtained in vivo from open-loop analysis in patients with disconnected feedback, i.e. with overt thyroid dysfunction or full dose substitution therapy with levothyroxine.

Conditions

Sponsors & Collaborators

  • Ruhr University of Bochum

    lead OTHER

Principal Investigators

  • Johannes W Dietrich, M.D. · Medical Hospital I, Bergmannsheil University Hospitals, Ruhr University of Bochum

  • Harald H Klein, M.D. · Medical Hospital I, Bergmannsheil University Hospitals, Ruhr University of Bochum

  • Johannes W Dietrich, M.D. · Medical Hospital I, Bergmannsheil University Hospitals, Ruhr University of Bochum

  • Bojana Bazika-Gerasch, M.D. · Medical Hospital I, Bergmannsheil University Hospitals, Ruhr University of Bochum

Eligibility

Min Age
14 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-06-01
Primary Completion
2018-07-31
Completion
2021-01-31

Countries

  • Germany

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01145040 on ClinicalTrials.gov