Metabolomics of Thyroid Hormones
NCT03823859 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 332
Last updated 2022-05-17
Summary
The aim of this study is to develop a metabolome signature of thyroid hormone status. The metabolome signature could be useful in diagnosis and treatment of thyroid dysfunction diseases, especially in cases where TSH cannot be reliably used.
Conditions
- Central Hypothyroidism
- Hypothyroidism
- Hyperthyroidism
Interventions
- DIAGNOSTIC_TEST
-
Indirect calorimetry
Resting energy expenditure
- DIAGNOSTIC_TEST
-
Dual energy X-ray Absorptiometry (DXA)
Body composition
- DIAGNOSTIC_TEST
-
Blood sampling
fT4, fT3, TSH, HDL, LDL, triglycerides, cholesterol, HbA1c, Glucose Thyroid panel
Sponsors & Collaborators
-
ETH Zurich
collaborator OTHER -
University Hospital, Basel, Switzerland
lead OTHER
Principal Investigators
-
Matthias Betz, PD Dr. med. · Klinik Endokrinologie, Diabetes und Metabolismus
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2018-12-12
- Primary Completion
- 2021-07-28
- Completion
- 2021-12-31
Countries
- Switzerland
Study Locations
More Related Trials
-
Effects of Thyroid Hormone Enzyme Blocking on Hypothyroidism
NCT01801033 ·Status: WITHDRAWN
-
Improvement of Laboratory Diagnostics in Hypothyroid Patients Using Levothyroxine
NCT06083636 ·Status: RECRUITING
-
Insulin Sensitivity and Metabolism Before and After Treatment in Patients With Hypothyroidism
NCT00770016 ·Status: TERMINATED ·Phase: NA
-
Throid Dysfunction in Liver Failure and Its Eddects Upon Outcome
NCT06179368 ·Status: RECRUITING
-
Study of Radioiodine (131-I) Uptake Following Administration of Thyrogen and Hypothyroid States During Thyroid Hormone Withdrawal.
NCT00001730 ·Status: COMPLETED ·Phase: PHASE4
-
Neurocognitive and Metabolic Effects of Mild Hypothyroidism
NCT00565864 ·Status: COMPLETED ·Phase: PHASE4
-
Thyroid Replacement Therapy in Patients With Subclinical Hypothyroidism
NCT04953195 ·Status: UNKNOWN ·Phase: PHASE4
-
Biosignals by Wearable Devices in Hypothyroidism
NCT04332770 ·Status: COMPLETED
-
The Influence of Different Thyroid Autoantibodies on Thyroid Function and Pregnancy Outcome After Assisted Reproductive Technology
NCT04019509 ·Status: UNKNOWN ·Phase: NA
-
Effect of Hypothyroidism on Brown Adipose Tissue
NCT02364102 ·Status: COMPLETED
-
Hypothyroidism, Metabolism and Quality of Life - Focus on QOL, REE, Cognitive Function and Body Composition
NCT02891668 ·Status: COMPLETED
-
Study of Thyrotropin-Releasing Hormone in Normal Volunteers and in Patients With Thyroid or Pituitary Abnormalities
NCT00054756 ·Status: COMPLETED ·Phase: PHASE2
-
Validation of a New TSH Test
NCT01997554 ·Status: COMPLETED ·Phase: NA
-
Metabolic Effects of Synthetic Thyroid Hormone for Thyroid Cancer Treatment
NCT01441154 ·Status: COMPLETED
-
Harmonization of Thyroid-stimulating Hormone Immunoassays Reagents
NCT05151120 ·Status: COMPLETED
-
The Effect of Thyroid Hormone on Drug Elimination in Cancer Patients
NCT00080574 ·Status: COMPLETED ·Phase: PHASE2
-
Hypothyroidism, Metabolism and Food Intake
NCT02993562 ·Status: COMPLETED
-
Effects of L-thyroxine Replacement on Serum Lipid and Atherosclerosis in Hypothyroidism
NCT01848171 ·Status: UNKNOWN ·Phase: PHASE4
-
The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid Cancer
NCT03841617 ·Status: RECRUITING ·Phase: PHASE2
-
Thyroid Study Type 2 Diabetes Mellitus (T2DM)
NCT01379170 ·Status: UNKNOWN ·Phase: PHASE4
-
Antithyroidal Antibodies With or Without Subclinical Hypothyroidism During Pregnancy in Infertile Women
NCT04249271 ·Status: COMPLETED
-
Resting Heart Rate Monitoring for Optimized Treatment and Surveillance of Hyperthyroidism
NCT04932135 ·Status: COMPLETED
-
The Impact of Pituitary-thyroid and Pituitary-adrenal Axes Function on COVID-19 Clinical Course.
NCT05070091 ·Status: COMPLETED
-
Effect of T4-T3 Combination Therapy Versus T4 Monotherapy in Patients With Hypothyroidism
NCT00531713 ·Status: COMPLETED ·Phase: PHASE4
-
Coexisting Thyroid Disease and Hyperparathyroidism
NCT01306916 ·Status: COMPLETED