MedTrace Logo

Strategy for Adequate Blood Pressure Lowering in the Patients With Intracranial Atherosclerosis

NCT01104311 · Status: TERMINATED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 132

Last updated 2017-03-07

Study results available
· View outcomes & findings →

Summary

To develop adequate blood pressure (BP) lowering strategy after subacute ischemic stroke patients with symptomatic severe intracranial atherosclerosis.

Primary hypothesis of this study is that aggressive BP control (lowering systolic BP between 110mmHg and 120mmHg) will not increase the ischemic lesion volumes in hemisphere compared to modest BP lowering (lowering systolic BP between 130mmHg and 140mmHg) in the patients with symptomatic severe intracranial atherosclerosis.

Conditions

  • Brain Ischemia

Interventions

PROCEDURE

Aggressive BP lowering

adjust the amount and number of antihypertensive drugs to lowering of systolic blood pressure to target level

PROCEDURE

modest blood pressure lowering

adjust the amount and number of antihypertensive drugs

Sponsors & Collaborators

  • Pfizer

    collaborator INDUSTRY

  • Asan Medical Center

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
40 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-04-30
Primary Completion
2014-04-30
Completion
2015-12-31

Countries

  • South Korea

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01104311 on ClinicalTrials.gov