Chronic Alcohol and Brain Stress Circuit Response
NCT01031264 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 120
Last updated 2015-07-30
Summary
Alcoholism is among the top three causes of preventable death and disease in the US (Mokdad et al., 2004; Room et al., 2005). Stress plays an important role in the development of alcoholism and in high vulnerability to alcohol relapse. This study will provide a greater understanding of the mechanism by which stress and alcohol consumption interacts to influence development of compulsive alcohol seeking and vulnerability to stress-induced drinking, and the results will have significant implications for the development of new prevention and treatment interventions for alcoholism.
Conditions
- Stress
- Alcoholism
Sponsors & Collaborators
-
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
collaborator NIH -
Yale University
lead OTHER
Principal Investigators
-
Rajita Sinha, PhD · Yale University
Eligibility
- Min Age
- 21 Years
- Max Age
- 50 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2009-01-31
- Primary Completion
- 2014-12-31
- Completion
- 2014-12-31
Countries
- United States
Study Locations
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