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Stress, Hypothalamic-pituitary-adrenal (HPA) Dysfunction, and Relapse in Alcoholism

NCT00744588 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 75

Last updated 2013-01-03

No results posted yet for this study

Summary

This proposal is part of the INIA Stress Consortium. This study will

1. explore the contributions of lifetime trauma, recent stress, and alcohol use on stress-hormone axis disruption in treatment seeking, one-month abstinent, alcohol-dependent subjects
2. assess the combined contributions of stress-hormone axis disruption and episodic stress on the risk of prospective drinking following treatment
3. determine the role of neurosteroids in alcohol use.

Conditions

  • Alcohol Dependence

Sponsors & Collaborators

  • Dallas VA Medical Center

    collaborator FED

  • National Institute on Alcohol Abuse and Alcoholism (NIAAA)

    collaborator NIH

  • University of Texas Southwestern Medical Center

    lead OTHER

Principal Investigators

  • Bryon Adinoff, MD · UT Southwestern Medical Center at Dallas and VA North Texas Health Care System

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-08-31
Primary Completion
2011-08-31
Completion
2012-03-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00744588 on ClinicalTrials.gov