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Cardiovascular Risk Assessment For Kidney Transplantation - Utility of Computed Tomography Coronary Angiography in the Assessment of Patients Awaiting Kidney Transplantation

NCT06234410 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 332

Last updated 2026-02-13

No results posted yet for this study

Summary

Cardiovascular disease (for example, heart attack, stroke, heart failure) is the commonest complication of kidney failure. Kidney transplantation reduces cardiovascular risk but cardiovascular disease remains the commonest cause of death in patients following transplantation.

Current strategies to assess patient's cardiovascular risk prior to kidney transplantation do not identify those at highest risk and do not improve outcomes.

This study will use a heart scan known as computed tomography coronary angiography (CTCA) to see whether this scan can identify patients at highest risk of future cardiovascular disease prior to transplantation. Studies have shown it is able to do this in patients with normal kidney function.

The aim of this study is to develop CTCA as an effective tool to risk stratify patients prior to kidney transplantation.

Conditions

Interventions

RADIATION

Computed tomography coronary angiography (CTCA)

Single CTCA scan prior to kidney transplantation

Sponsors & Collaborators

  • Chief Scientist Office of the Scottish Government

    collaborator OTHER_GOV

  • University of Glasgow

    collaborator OTHER

  • NHS Lothian

    collaborator OTHER_GOV

  • NHS Greater Glasgow and Clyde

    collaborator OTHER

  • University of Edinburgh

    lead OTHER

Principal Investigators

  • Neeraj Dhaun, MBChB · University of Edinburgh

Eligibility

Min Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-01-24
Primary Completion
2032-01-31
Completion
2032-01-31

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06234410 on ClinicalTrials.gov