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Study on the Development of Opioid Induced Hyperalgesia (OIH) After Exposure to Alfentanil

NCT00991809 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 22

Last updated 2017-10-06

Study results available
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Summary

The purpose of this study was to follow a person's response to experimental pain after multiple consecutive exposures to alfentanil or diphenhydramine to see if the person can tolerate the pain more, less, or the same at the end of the study.

Conditions

  • Hyperalgesia

Interventions

DRUG

Alfentanil

15 mcg/kg IM

DRUG

Diphenhydramine

25 mg IM

Sponsors & Collaborators

Principal Investigators

  • David A Tompkins, M.D. · Johns Hopkins University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2009-02-28
Primary Completion
2010-05-31
Completion
2010-05-31

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00991809 on ClinicalTrials.gov