Biomarkers in Patients at Risk of Developing Myelodysplastic Syndrome or Other Disorders and in Healthy Participants
NCT00899327 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2009-07-08
Summary
RATIONALE: Studying samples of blood and bone marrow in the laboratory from patients at risk of developing myelodysplastic syndrome may help doctors learn more about changes that occur in DNA and identify biomarkers related to disorders of the blood and bone marrow.
PURPOSE: This research study is looking at biomarkers in patients at risk of developing myelodysplastic syndrome or other disorders and in healthy participants.
Conditions
Interventions
- GENETIC
-
DNA methylation analysis
- GENETIC
-
RNA analysis
- GENETIC
-
cytogenetic analysis
- GENETIC
-
gene expression analysis
- GENETIC
-
mutation analysis
- GENETIC
-
polymerase chain reaction
- GENETIC
-
protein expression analysis
- OTHER
-
laboratory biomarker analysis
Sponsors & Collaborators
-
Oxford University Hospitals NHS Trust
lead OTHER
Principal Investigators
-
Vyas Paresh, MD · Oxford University Hospitals NHS Trust
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2007-01-31
- Primary Completion
- 2011-12-31
Countries
- United Kingdom
Study Locations
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