DNA in Predicting Response After Systemic Therapy in Women With Metastatic Breast Cancer
NCT00899548 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 182
Last updated 2019-07-26
Summary
RATIONALE: Studying samples of blood from patients with cancer and from healthy participants in the laboratory may help doctors learn more about changes that may occur in DNA and identify biomarkers related to cancer. It may also help doctors predict how well patients will respond to systemic therapy.
PURPOSE: This laboratory study is looking at DNA in predicting response after systemic therapy in women with metastatic breast cancer.
Conditions
Interventions
- GENETIC
-
DNA methylation analysis
laboratory analysis
- GENETIC
-
microarray analysis
laboratory analysis
- GENETIC
-
polymerase chain reaction
laboratory analysis
- OTHER
-
laboratory biomarker analysis
laboratory analysis
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
lead OTHER
Principal Investigators
-
Antonio C. Wolff, MD · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2007-01-31
- Primary Completion
- 2010-06-30
- Completion
- 2016-10-31
Countries
- United States
Study Locations
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